Identification and Characterization of Novel Superantigens from Streptococcus pyogenes
نویسندگان
چکیده
منابع مشابه
Identification and Characterization of Novel Superantigens from Streptococcus pyogenes
Three novel streptococcal superantigen genes (spe-g, spe-h, and spe-j) were identified from the Streptococcus pyogenes M1 genomic database at the University of Oklahoma. A fourth novel gene (smez-2) was isolated from the S. pyogenes strain 2035, based on sequence homology to the streptococcal mitogenic exotoxin z (smez) gene. SMEZ-2, SPE-G, and SPE-J are most closely related to SMEZ and strepto...
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Objective(s): Streptococcus pyogenes, a notorious human pathogen is responsible to cause a wide range of infections varies from superficial common clinical illness to severe and life threatening infections. To our knowledge this is the first report exploring the emm types and superantigen/exotoxin gene profile of S. pyogenes from Pakistan. Materials a...
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Streptococcus pyogenes appears to be almost exclusively restricted to humans, with few reports on isolation from animals. We provide a detailed characterization (emm typing, pulsed-field gel electrophoresis [PFGE], and multilocus sequence typing [MLST]) of 15 S. pyogenes isolates from animals associated with different clinical backgrounds. We also investigated erythromycin resistance mechanisms...
متن کاملMolecular Characterization of Streptococcus pyogenes Isolated from Children with Pharyngitis
Submit Manuscript | http://medcraveonline.com [1]. Streptococcal pharyngitis is most significant disease, and its peak incidence occurs in children, these infections impose the economic burden on the society [2]. The symptoms of streptococcal pharyngitis include a sore throat, pain in swallowing, fever, swollen, and tender lymph nodes in the neck and fatigue [3]. S. pharyngitis oftenly results ...
متن کاملMolecular Characterization of Streptococcus pyogenes Isolated from Children with Pharyngitis
Submit Manuscript | http://medcraveonline.com [1]. Streptococcal pharyngitis is most significant disease, and its peak incidence occurs in children, these infections impose the economic burden on the society [2]. The symptoms of streptococcal pharyngitis include a sore throat, pain in swallowing, fever, swollen, and tender lymph nodes in the neck and fatigue [3]. S. pharyngitis oftenly results ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1999
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.189.1.89